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Do you wonder, Why does IVF fl? The success stories of in-vitro fertilization IVF treatments often shine a light on the triumphs of those who are eager to become parents. However, it's less commonly discussed that not every attempt at IVF is successful, often due to emotional subjects that many find hard to talk about openly. breaks this taboo by exploring some of the reasons behind the flure of IVF procedures.
Our latest success rates, as submitted to the Fertilisation and Embryology Authority HFEA, show a clinical pregnancy rate of 40.6 and live birth rate of 32.5. For patients who do not achieve either outcome, there are various reasons their IVF attempts have been unsuccessful.
Age Factor
As women age, the quality and quantity of their eggs decrease, leading to diminished chances of pregnancy through IVF treatments due to this decline in egg health. Dr. Gorgy, co-founder of The Fertility and Gynaecology Academya distinguished fertility consultant recognized across the UKhighlights that for patients under 35 years old, our success rates are highest: a clinical pregnancy rate of 47 and live birth rate at 38.
Embryo Quality
In the laboratory setting during IVF treatment, eggs from women and sperm from men are combined to create embryos. Some embryos may seem healthy in the lab but might fl to implant into the uterus due to unseen defects not visible through standard assessments. Our IVF Lab uses an embryo grading system alongside time-lapse imaging embryoscope to monitor embryo development until day 5, which includes incubating embryos with cameras that record every movement and dividing process.
Reproductive issues can occur if there are problems with egg quality, sperm, or the uterus, making it challenging for the embryo to implant successfully. Dr. Gorgy explns that embryos from women over age 35 are more likely to have chromosomal abnormalities, which may be why this is a common reason among this demographic.
Chromosomal Abnormalities
These genetic anomalies are primarily found in embryos of older patients and result from errors during the cell division process. Fortunately, by testing all 23 prs of chromosomes for inherited disorders or gene abnormalities before embryo transfer can help ensure only normal embryos proceed.
Embryo Transfer Risk
Even if an IVF cycle is successful to reach this stage, there's still a risk of miscarriage or other issues that could lead to another unsuccessful attempt. This underscores the importance of having multiple attempts when necessary, as understanding what went wrong in previous cycles can inform strategies for future success.
Reproductive Immunology
This theory suggests that an embryo or fetus might be rejected due to overactive immune cells within the body. If you have previously fled IVF cycles without a successful birth, it could indicate that your immune system is attacking the embryo.
Next Steps: Reducing Risk of Recurrent Flure
Repeating unsuccessful IVF cycles can take a toll physically, emotionally, and mentally on patients. However, knowing you are not alone in your struggle brings relief when there's help avlable from experienced fertility experts who understand these complexities.
With each new attempt at IVF, doctors will advise on the causes for previous flure to improve success chances if undergoing treatment agn. Several tests can be carried out by a healthcare team to identify potential issues:
Immune Testing
Infection Screening
Uterine Cavity Assessment
Chromosomal Analysis Karyotyping
Sperm Evaluation
If you have further questions about IVF, our embryologists and physicians are here to assist. You can reach us by calling 020 7224 1880 or book an online consultation for personalized guidance.
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